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Dr. Asish Pal

Associate Professor (Scientist-E)

Development of supramolecular polymeric hydrogel based biomaterials, Stimuli-responsive materials for controlled release and delivery, Dynamic combinatorial chemistry for self-healing and functional nanomaterials, Multivalent recognition for imaging and diagnostic application

CONTACT INFORMATION :

Research Interest

  • Multivalent molecular probe: Taking lesson from nature, molecular probe with enhanced binding affinity will be designed for application in imaging and diagnostic application

  • Hydrogels: Self-assembled organic and polymeric hydrogel materials will be developed for biomedical applications such as tissue engineering, biomimetic adhesive.

  • Nanocontainer: Single chain polymeric nanoparticles with stimuli-responsiveness will be designed towards development of efficient catalytic nanocontainer in persuit of mimicking enzymes and in designing self-healing materials.

Research Highlights

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PhD Students

  • Ms. ANTARLINA MAULIK

    Email: antarlina.ph20202@inst.ac.in

    Reg. No.: PH20202

    Working Since Aug, 2020

  • Mr. Jojo P Joseph

    Email: jojo.ph15211@inst.ac.in

    Reg. No.: PH15211

    Working Since Aug, 2015

  • Ms. Deepika Gupta

    Email: deepika.ph16216@inst.ac.in

    Reg. No.: PH16216

    Working Since Aug, 2016

  • Mr.Chirag Miglani

    Email: chirag.ph17229@inst.ac.in

    Reg. No.: PH17229

    Working Since Jan, 2018

  • Ms. Nimisha Atul Mavlankar

    Email: nimisha.ph19215@inst.ac.in

    Reg. No.: PH19215

    Working Since Aug, 2019

PhD Students

  • Mr. Ashmeet Singh

    Email: ashmeet.ph14207@inst.ac.in

    Reg. No.: PH14207


  1. Enzyme Responsive Chiral Self-sorting in Amyloid-inspired Minimalistic Peptide Amphiphiles: Deepika Gupta, Ranjan Sasmal, Ashmeet Singh, Jojo P. Joseph, Chirag Miglani, Sarit S. Agasti, Asish Pal, (2020) Nanoscale, 12: 18692 - 18700. DOI: 10.1039/D0NR04581K

  2. Photoresponsive Chain Collapse in Flexo-rigid Functional Copolymer to Modulate Self-healing Behavior: Jojo P. Joseph,Chirag Miglani,Ashmeet Singh,Deepika Gupta,Asish Pal, (2020) Soft Matter, 16: 2506-2515. DOI: 10.1039/D0SM00033G

  3. Tandem Interplay of Host-guest Interaction and Photo-responsive Supramolecular Polymerization to 1D and 2D Functional Peptide Materials: Jojo P Joseph, Ashmeet Singh,Deepika Gupta, Chirag Miglani,Asish Pal, (2019) ACS Applied Mater Interface, 11: 28213-28220. DOI: 10.1021/acsami.9b09690

  4. Supramolecular Gels from Sugar-linked Triazole Amphiphiles for Drug Entrapment and Release for Topical Application: Komal Sharma, Jojo P. Joseph, Adarsh Sahu, Narender Yadav, Mohit Tyagi, Ashmeet Singh,Asish Pal,K. P. R. Kartha, (2019) RSC Advances, 9: 19819 - 19827. DOI: 10.1039/C9RA02868D

  5. Pathway Driven Self-assembly and Living Supramolecular Polymerization in Amyloid-inspired Peptide Amphiphile,: Ashmeet Singh, Jojo P. Joseph, Deepika Gupta,Indranil Sarkar,Asish Pal, (2018) Chemical Communications, 54: 10730-10733. DOI: 10.1039/C8CC06266H

  6. Chirality control to multi-stimuli responsive and self-healing supramolecular metallo-hydrogels: Bhagwati Sarma,Ashmeet Singh,Tridib K. Sarma,Neha Sardana,Asish Pal, (2018) New J. Chem, 42: 6427-6432. DOI: 10.1039/C8NJ00218E

  7. Mechanism of Building Block Exchange in Stacks of Self-replicating Macrocycles: Elio Mattia,Giulia Leonetti,Sijbren Otto,Asish Pal, (2017) Synlett, 28: 103-107. DOI: 10.1055/s-0036-1589709

  8. Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: M. Yagiz Unver,Matthijs Bakker, Stephan P. Berrier, Anna K. H. Hirsch,Asish Pal,Milon Mondal, (2016) Chem. Eur. J., 22: 14826–14830. DOI: 10.1002/chem.201603001

  9. Multi-step control over self-assembled hydrogels of peptide-derived building blocks and a polymeric cross-linker: Van Duc Nguyen, Frank Snijkers, Mathieu Colomb-Delsuc, Giulia Leonetti, Sijbren Otto, Jasper van der Gucht.,Asish Pal, (2016) Soft Matter, 12: 432-440. DOI: 10.1039/C5SM02088C

  10. Controlling the Structure and Length of Self-synthesizing Supramolecular Polymers through Nucleated Growth and Disassembly: Morteza Malakoutikhah, Giulia Leonetti, Meniz Tezcan, Mathieu Colomb-Delsuc, Van Duc Nguyen, Jasper van der Gucht, Sijbren Otto,Asish Pal, (2015) Angew. Chem. Int. Ed., 54: 7852-7856. DOI: 10.1002/anie.201501965

  11. Topochemical Polymerization in Self-assembled Rodlike Micelles of Bisurea Bolaamphiphiles: Panayiotis Voudouris, Marcel. M. E. Koenigs, Pol Besenius, Hans M. Wyss, Volkan Degirmenci, Rint P. Sijbesma.,Asish Pal, (2014) Soft Matter, 10: 952-956. DOI: 10.1039/C3SM52605D

  12. Tuning Crosslink Density in a Physical Hydrogel by Supramolecular Self-sorting.: Marcel Koenigs,Hamed Mortazavi, Gajanan Pawar, Kees Storm, Rint P. Sijbesma,Asish Pal, (2014) Macromolecules, 47: 2712-2717. DOI: 10.1021/ma500446g

  13. SANS Studies of Mixed Micellar Structures made of Dimeric Surfactants having Imidazolium and Ammonium Headgroups: Sougata Dutta, V. K. Aswal,Santanu Bhatttacharya,Asish Pal, (2012) J. Phys. Chem. B, 116: 13239-13247. DOI: 10.1021/jp304700t

  14. Self-Sorting in Rodlike Micelles of Chiral Bisurea Bolaamphiphiles: Pol Besenius, Rint P. Sijbesma.,Asish Pal, (2011) J. Am. Chem. Soc, 133: 12987-12989. DOI: 10.1021/ja205345e

  15. An Insight into Fiber-Solvent Mediated Modulation of Nano-fibrillar Organogels: Suman K. Samanta,Santanu Bhatttacharya,Asish Pal, (2011) Int. J. Nanosci., 10: 547-554. DOI: 10.1142/S0219581X11009374

  16. Carbon nanotube reinforced supramolecular gels with electrically conducting, viscoelastic and near-infrared sensitive properties: Suman K. Samanta,Santanu Bhattacharya, C.N.R. Rao,Asish Pal, (2010) J. Mater. Chem., 20: 6881-6890. DOI: 10.1039/C0JM00491J

  17. Coexisting Hydrophobic Compartments through Self-Sorting in Rod-like Micelles of Bisurea Bolaamphiphiles.: S. Karthikeyan, Rint P. Sijbesma,Asish Pal, (2010) J. Am. Chem. Soc, 132: 7842-7843. DOI: 10.1021/ja101872x

  18. Role of Capping Ligands on the Nanoparticles in the Modulation of Properties of a Hybrid Matrix of Nanoparticles in a 2D Film and in a Supramolecular Organogel.: Asish Pal,Santanu Bhattacharya, (2009) Chem. Eur. J., 15: 9169-9182. DOI: 10.1002/chem.200900304

  19. Structure and properties of two component hydrogels comprising lithocholic acid and organic amines: Hajra Basit, Saikat Sen, Vinod K. Aswal, Santanu Bhattacharya,Asish Pal, (2009) J. Mater. Chem, 19: 4325-4334. DOI: 10.1039/B903407B

  20. Choice of the End Functional Groups in Oligo(p-Pheylenevinylene) Systems Controls the Physical Gelation Efficiency.: Suman K. Samanta,Asish Pal,Santanu Bhattacharya, (2009) Langmuir, 25: 8567-8578. DOI: 10.1021/la8036154

  21. Two Component Hydrogels Comprising Fatty Acids and Amines: Structure, Properties and Application as Template for Metal Nanoparticle Synthesis: Hajra Basit,Asish Pal,Saikat Sen,Santanu Bhattacharya, (2008) Chem. Eur. J., 14: 6534-6545. DOI: 10.1002/chem.200800374

  22. Physical Gelation of Binary Mixtures of Hydrocarbons Mediated by n-Lauroyl-L-Alanine and Characterization of their Thermal and Mechanical Properties: Santanu Bhattacharya,Asish Pal, (2008) J. Phys. Chem. B, 112: 4918-4927. DOI: 10.1021/jp7104715

  23. Synthesis and Properties of Novel Nanocomposites made of Single-Walled Carbon Nanotubes and Low Molecular Mass Organogels and their Thermo-responsive Behavior Triggered by Near IR Radiation: Bhupender S. Chhikara, A. Govindaraj, Santanu Bhattacharya, C.N.R. Rao,Asish Pal, (2008) J. Mater. Chem., 18: 2593-2600. DOI: 10.1039/B719432C

  24. Molecular mechanism of physical gelation of hydrocarbons by fatty acid amides of natural amino acids: Yamuna K. Ghosh,Asish Pal,Santanu Bhattacharya, (2007) Tetrahedron, 63: 7334-7348. DOI: 10.1016/j.tet.2007.05.028

  25. Modulation of Viscoelastic Properties of Physical Gels by Nanoparticle Doping: Influence of the Nanoparticle Capping Agent.: Santanu Bhattacharya, Aasheesh Srivastava,Asish Pal, (2006) Angew. Chem. Int. Ed., 45: 2934-2937. DOI: 10.1002/anie.200504461

  1. Self-healing materials from crystalline polymer composites: Jojo P. Joseph,Ashmeet Singh,Asish Pal, (2017) Springer, Switzerland, 181-218.

  1. Self-synthesizing materials with narrow length distribution through living supramolecular polymerization: Giulia Leonetti, Mathieu Colomb-Delsuc, Jasper van der Gucht, Sijbren Otto,Asish Pal, (2014) .

  2. Tuning the Properties of Photo-induced Hydrogels Obtained from Self-Replicating Peptide Fibers: Jianwei Li, Mathieu Coulomb-Delsuc, Morteza Malakoutikhah, Sijbren Otto,Asish Pal, (2013) .

  3. Towards Out-of-equilibrium Self-assembly:: Jianwei Li, Sijbren Otto, (2012) .

  4. Enantiomeric compartments through self-sorting of rod-like micelles of chiral bisurea bolaamphiphiles: Asish Pal,Rint P. Sijbesma, (2011) .

  5. Dynamic Hydrophobic Compartments through Self-sorting of Rod-like Micelles of Bisurea Bolaamphiphiles: presentation in Dutch Polymer Days, (2010) .

  6. Delineating the Influence of Capping Agents on Metal Nanoparticle-Low Molecular Mass Gel composites: Barbara, USA in Aug, (2007) .

Fundings

  • Development of advanced third generation matrix associated chondrocytes for cartilage repair 3 years, DBT-Biocare
    Funding Amount: 174 Lakh
    PI: Dr. Asish Pal
  • SANS study to probe collapse of Single Chain Polymer into discrete Nanoparticles 3 years, UGC-DAE-CSR
    Funding Amount: 1.35 lakh
    PI: Dr. Asish Pal
  • Surface modification for better adhesion property between rubber and textiles 1.5 years, SRF Industrial Project
    Funding Amount: 30 Lakh
    PI: Dr. Asish Pal
  • Stimuli-responsive collapse of tailored single chain functional polymer to diverse hierarchical nanostructures for catalysis and self-healing applications 3 years, SERB-ECR
    Funding Amount: 39.96 Lakh
    PI: Dr. Asish Pal

  • 2009

    PhD: Department of Organic Chemistry

    Indian Institute of Science (IISc), Bangalore, India

  • 2004

    MS: Chemical Science Division

    Indian Institute of Science (IISc), Bangalore, India

  • 2001

    BSc

    University of Calcutta, India

  • Associate Professor (Scientist-E):Chemical Biology Unit, Institute of Nano Science & Technology, Mohali, India (May 2015 to Present till date )

  • Postdoctoral Research Fellow with Prof. Sijbren Otto:Stratingh Institute of Chemistry, University of Groningen, The Netherlands (March 2012 to March 2015 )

  • Postdoctoral Research Fellow with Prof. Rint P. Sijbesma:Molecular Science & Technology, Eindhoven University of Technology, Eindhoven, The Netherlands (March 2009 to March 2012 )

Awards & Honours

  • Young Scientist from ECOST

  • National Eligibility Test (NET) from CSIR-UGC

  • IISc Integrated PhD fellowship


Professional Recognitions

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