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Dr. Manish Singh

Scientist-C

Confocal  and  Electron  Microscopy,  Cellular  and  Molecular Neuroscience,  In-utero Exposures and CNS Development, Behavioral Neurology.

CONTACT INFORMATION :

Research Interest

  • Research interests of my group include Cellular and  Molecular  Neuroscience,  In  utero Exposures and CNS Development, Neuro-Behavioral Analysis, Nanoneurotoxicology,  Developmental Nanotoxicology, Nano Environmental Health and Safety and Bioimaging Tools (Confocal and Electron Microscopy). We are currently working on toxicology of nanomaterials like GO with a special focus on their hazardous effects on reproductive, fetal and long term behavioural outcomes. We are also exploring the applications of piezoelectric nanomaterials and physical stimulation strategies for enhancement of neuritic outgrowth and neuronal regeneration.

Research Highlights

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PhD Students

  • MS. MEHAK KAMBOJ

    Email: mehak.ph20204@inst.ac.in

    Reg. No.: PH20204

    Working Since Aug, 2020

  • Mr. Prashant Sharma

    Email: prashant.ph19237@inst.ac.in

    Reg. No.: PH19237

    Working Since Jan, 2020

  • Mr. Indranil De

    Email: indranil.ph19227@inst.ac.in

    Reg. No.: PH19227

    Working Since Jan, 2020

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  1. Effect of galvanotaxic graphene oxide on chloroplast activity: Interaction quantified with Biolayer-Interferometry coupled confocal microscopy: Sharma S., Sahu B., Srinivasan S., Singh M., G. Jayamurugan., Vijayakumar S.*, (2020) Carbon, 162: 147-156. DOI: 10.1016/j.carbon.2020.02.054

  2. Gold Nano-/Microroses on Levodopa Microtubes for SERS-Based Sensing of Gliomas: T Dube, N Kumar, A Kour, J Mishra, Manish Singh, B Prakash, JJ Panda, (2019) ACS Applied Nano Materials, 2 (5),: 2663-2678.. DOI: 10.1021/acsanm.9b00155

  3. Effects of prenatal exposure to antipsychotic risperidone on developmental neurotoxicity, apoptotic neurodegeneration and neurobehavioral sequelae in rat offspring.: Singh KP,Singh MK, (2016) Int J Dev Neurosci., 52: 13-23. DOI: 10.1016/j.ijdevneu.2016.05.006

  4. Efficient MoS2 exfoliation by cross beta amyloid nanotubes for multi stimuli responsive and biodegradable aqueous dispersions.: idhi Kapil, Asmeet Singh,Dibyendu Das., (2016) Angew Chem Int Ed Engl., 55(27): 7772-6.. DOI: 10.1002/anie.201509953

  5. Assessment of in-utero Venlafaxine induced, ROS-mediated, apoptotic neurodegeneration in fetal neocortex.: K.P. Singh,Shubha Shukla , Madhu Dikshit., (2015) Int J Dev Neurosci., 40: 60-91. (IF-2.58). DOI: 10.1016/j.ijdevneu.2014.10.007

  6. Impact on maternal, fetal, postnatal growth and possible birth defects in rat offspring: K.P. Singh, (2013) Natl Acad Sci Let., 36 (1): 35-40 (IF-0.29). DOI: 10.14336/AD.2014.05001

  7. Consequences of Alteration in Leucine Zipper Sequence of Melittin in Its Neutralization of Lipopolysaccharide-induced Proinflammatory Response in Macrophage Cells and Interaction with Lipopol: aghvendra M. Srivastava, Saurabh Srivastava, Manish Singh, Virendra Kumar Bajpai,Jimut Kanti Ghosh, (2012) J. Biol. Chem., 287(3): 1980-95 (IF-4.57). DOI: 10.1074/jbc.M111.302893

  8. Inducing toxicity by introducing a leucine-zipper-like motif in frog antimicrobial peptide, magainin 2: Brijesh Kumar Pandey, Saurabh Srivastava,Jimut Kanti Ghosh., (2011) Biochem. J., 436: 609–620(IF-4.39). DOI: 10.1042/BJ20110056

  9. Effect of hypothyroxinemia on thyroid hormone responsiveness and action during rat postnatal neocortical development.: Satish Babu, Rohit Anthony Sinha, Vishwa Mohan, Geeta Rao, Amit Pal, Amrita Pathak, Madan M. Godbole., (2011) Exp. Neurol., 228(1): 91-98. (IF-4.69. DOI: 10.1016/j.expneurol.2010.12.012

  10. Functional and Molecular Characterization of NOS Isoforms in Rat Neutrophil Precursor Cells.: Anupam Jyoti, Ravi Shankar Keshari,Manoj Kumar Barthwal, Madhu Dikshit.,Sachin Kumar, (2010) Cytometry A, 77(5): 467-77 (IF-2.9). DOI: 10.1002/cyto.a.20852

Fundings

  • Glioma Targeting Anticancer Peptide Theranostic Nanoparticles. 3 years, DBT Biocare
    Funding Amount: Rs 52 Lakhs
    PI: Dr. Manish Singh Co-PI: Dr. Jiban Jyoti Panda
  • Assessment of maternal, reproductive and fetal toxicity induced by intrauterine exposure of carbonaceous nanomaterials like graphene and carbon nanotubes. 39 months, SERB (DST)
    Funding Amount: Rs.22.24 lakhs
    PI: Dr. Manish Singh

  • 2013

    Doctor of Philosophy From Neurobiology Lab., Department of Zoology

    University of Allahabad

  • 2013

    Post Graduate Diploma in Intellectual Property Rights

    IGNOU

  • 2005

    Master of Science

    University of Allahabad

  • 2003

    Bachelor of Science

    University of Allahabad

  • Worked in Neurobiology Lab., Department of Zoology as Research Scholar:University of Allahabad, Allahabad (January 2005 to January 2007 )

  • Worked in Electron Microscopy Unit as Technical Assistant (Confocal Microscopy):CSIR-Central Drug Research Institute, Lucknow (January 2008 to January 2012 )

  • Worked in Division of Science & Technology Management:CSIR-Central Drug Research Institute, Lucknow as Technical Assistant (March 2012 to March 2014 )

Awards & Honours

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Professional Recognitions

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