Faculty Directory

Dr. Jayamurugan Govindasamy

Associate Professor (Scientist-E)

New synthetic methods, Functional organic materials, Supramolecular chemistry, Polymer chemistry. The research in my group is centred on synthetic organic chemistry with a view to exploring nanoporous and nanomaterials for various types of applications ranging from energy, catalysis, sensing, and Nanotherapeutics. Thus, it is highly interdisciplinary in nature. The general strategy of our research is designing and synthesizing the functional nanomaterials with targeted applications and understanding the properties by applying state-of-the-art characterization techniques.

CONTACT INFORMATION :

Research Interest

  • Design and synthesis and photophysical property studies of Push-Pull Chromophores

           Synthetic Methodology

           Sensing

           Bio-imaging

           Opto-electronic applications

           White-light emission

           Perovskite Solar Cell

           As Photosensitizer in Catalysis

     

    Catalysts Design, Synthesis, and Studies

           Organic Transformation Reactions

           Biomass conversion

           Photocatalysis

           Dye/pollutant degradation

     

    Customized Polymeric Nanoformulation

           Drug Delivery (Cancer therapy)

           Pesticide Delivery (Agriculture)

           Anti-microbial coating (Healthcare)

Research Highlights

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PhD Students

  • MR. RAINA SHARMA

    Email: raina.ph20227@inst.ac.in

    Reg. No.: PH20227

    Working Since Aug, 2020
  • Mr. Abdul Selim

    Email: abdul.ph16219@inst.ac.in

    Reg. No.: PH16219

    Working Since Aug, 2016
  • Mr. Arif Hassan Dar

    Email: arif.ph15216@inst.ac.in

    Reg. No.: Ph15216

    Working Since Jan, 2016
  • Ms. Shaifali Sartaliya

    Email: shaifali.ph16232@inst.ac.in

    Reg. No.: PH16232

    Working Since Jan, 2017
  • Ms. Neethu K M

    Email: neethu.rp251722@inst.ac.in

    Reg. No.: PH251722

    Working Since Jan, 2018

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  1. Synthesis of 1,1,4,4‐Tetracyanobuta‐1,3‐Dienes using Tetracyanoethylene Oxide via [3+2]‐Cycloaddition‐Ring Opening Reaction: A. H. Dar, V. Gowri, K. M. Neethu, G. Jayamurugan*, (2020) ChemistrySelect, 5: 12437-12441. DOI: 10.1002/slct.202003179

  2. Synergistic Effects of Carbon Dots and Palladium Nanoparticles Enhance the Sonocatalytic Performance for Rhodamine B Degradation in the Absence of Light: Abdul Selim, Sharanjeet Kaur, Arif Hassan Dar, Shaifali Sartaliya, and Govindasamy Jayamurugan*, (2020) ACS Omega, 56: 22603-22613. DOI: 10.1021/acsomega.0c03312

  3. Comparative Acute Intravenous Toxicity Study of Triple Polymer Layered Magnetic Nanoparticles with Bare Magnetic Nanoparticles in Swiss Albino Mice: Anas Ahmad, Md. Meraj Ansari, Ajay Kumar, Akshay Vyawahare, Rakesh Kumar Mishra, Govindasamy Jayamurugan, Syed Shadab Raza, Rehan Khan*, (2020) Nanotoxicology, NA: Accepted.

  4. Effect of galvanotaxic graphene oxide on chloroplast activity: Interaction quantified with Biolayer-Interferometry coupled confocal microscopy: Sharma S., Sahu B., Srinivasan S., Singh M., G. Jayamurugan., Vijayakumar S.*, (2020) Carbon, 162: 147-156. DOI: 10.1016/j.carbon.2020.02.054

  5. Tuning of the Cross-Glaser Products mediated by Substrate-Catalyst’s Polymeric Backbone Interactions: S. Kuar, A. Mukhopadhyaya, A. Selim, V. Gowri, K. M. Neethu, A. H. Dar, S. Sartaliya, M. E. Ali*, G. Jayamurugan*, (2020) Chem. Commun., 56: 2582-2585. DOI: 10.1039/C9CC08565C

  6. Hyperbranched polymer-functionalized magnetic nanoparticles mediated hyperthermia and niclosamide bimodal therapy of Colorectal Cancer Cells.: A Ahmad, A Gupta, MM Ansari, A Vyawahare, G Jayamurugan*, R. Khan*, (2019) ACS Biomater. Sci. Eng., 6: 1102-1111. DOI: 10.1021/acsbiomaterials.9b01947

  7. Designing of Push-Pull Chromophores with Tunable Electronic and Luminescent Properties using Urea as Electron Donor: A. H. Dar, V. Gowri, A. Gopal, A. Muthukrishnan, A. Bajaj, S. Sartaliya, A. Selim, M. E. Ali, G. Jayamurugan*, (2019) The Journal of Organic Chemistry, 84: 8941 - 8947. DOI: 10.1021/acs.joc.9b00841

  8. Nanocarrier Composed of Magnetite Core Coated with Three Polymeric Shells Mediates LCS-1 Delivery for Synthetic Lethal Therapy of BLM-Defective Colorectal Cancer Cells: A. Gupta, A. AHMAD, H. Singh, S. Kaur, Neethu K M, M. M. Ansari, G. Jayamurugan*, R. Khan*, (2018) Biomacromolecules, 19: 803-815. DOI: 10.1021/acs.biomac.7b01607

  9. Design and Synthesis of Aviram–Ratner-Type Dyads and Rectification Studies in Langmuir–Blodgett (LB) Films: V. Gowri, D. Hernández, S. Martin, A. González-Orive, C. Dengiz, O. Dumele, F. Pérez-Murano, J.-P. Gisselbrecht, C. Boudon, W. B. Schweizer, B. Breiten, A. D. Finke, G. Jeschke, B. Bernet, L. Ruhlmann, P. Cea, F. Diederich, (2016) Chem. Eur. J., 22: 10539-10547. DOI: 10.1002/chem.201505216

  10. Selective endo and exo binding of mono- and ditopic-ligands to a rhomboidal diporphyrin prism: D. A. Roberts, T. K. Ronson, J. R. Nitschke, (2015) Angew. Chem. Int. Ed., 54: 7539-7543. DOI: 10.1002/anie.201501359

  11. Size and Energy Level Tuning of Quantum Dot Solids via a Hybrid Ligand Complex: M. L. Böhm, T. C. Jellicoe, J. P. H. Rivett, A. Sadhanala, N. J. L. K. Davis, F. S. F. Morgenstern, K. C. Gödel, C. G. M. Benson, N. C. Greenham, B. Ehrler, (2015) J. Phys. Chem. Lett., 6: 3510−3514. DOI: 10.1021/acs.jpclett.5b01751

  12. Enhancement of immunogenicity and efficacy of a plasmid DNA rabies vaccine by nanoformulation with a fourth-generation amine-terminated poly(ether imine) dendrimer: P. T. Ullas, S. N. Madhusudana, A. Desai,N. Jayaraman, (2014) Int. J. Nanomedicine, 9: 627–634. DOI: 10.2147/IJN.S53415

  13. One-Pot access to push-pull oligoenes by sequential [2+2] cycloaddition–retroelectrocyclization reactions: A. D. Finke, J.-P. Gisselbrecht, C. Boudon, W. B. Schweizer, F. Diederich, (2014) J. Org. Chem, 79: 426–431. DOI: 10.1021/jo402440m

  14. Expanding the chemical structure space of optoelectronic molecular materials: unprecedented push–pull chromophores by reaction of a donor-substituted tetracyanofulvene with electron-rich alky: O. Dumele, J.-P. Gisselbrecht, C. Boudon, W. B. Schweizer, B. Bernet, F. Diederich, (2013) J. Am. Chem. Soc., 135: 3599–3606.. DOI: 10.1021/ja312084s

  15. Photophysical behavior of poly(propyl ether imine) dendrimer in the presence of nitroaromatic compounds: R. S. Bagul, Y. B. R. D. Rajesh, A. Bera, A. K. Sood, N. Jayaraman, (2013) J. Photochem. Photobiol., A, 253: 1–6. DOI: 10.1016/j.jphotochem.2012.12.011

  16. 6,6-Dicyanopentafulvenes: Electronic structure and regioselectivity in [2 + 2] cycloaddition–retroelectrocyclization reactions: A. D. Finke, O. Dumele, M. Zalibera, D. Confortin, P. Cias, J.-P. Gisselbrecht, C. Boudon, W. B. Schweizer, G. Gescheidt, F. Diederich, (2012) J. Am. Chem. Soc, 134: 18139–18146. DOI: 10.1021/ja309141r

  17. Expanding the chemical space for push-pull chromophores by non-concerted [2+2] and [4+2] cycloadditions: access to a highly functionalized 6,6-dicyanofulvene with an intense low-energy charge: J.-P. Gisselbrecht, C. Boudon, F. Schoenebeck, W. B. Schweizer, B. Bernet, F. Diederich, (2011) Chem. Commun., 47: 4520–4522. DOI: 10.1039/C1CC10247H

  18. Interaction of single-walled carbon nanotubes with poly(propyl ether imine) dendrimers: K. S. Vasu, Y. B. R. D. Rajesh, S. Kumar, V. Vasumathi, P. K. Maiti, A. K. Sood, N. Jayaraman, (2011) J. Chem. Phys., 134: 104507/1–104507/6. DOI: 10.1063/1.3561308

  19. Dendritic poly(ether imine) based gene delivery vector: U. P. Thankappan, S. N. Madhusudana, A. Desai, Y. B. R. D. Rajesh, N. Jayaraman, (2011) Bioconjugate Chem, 22: 115–119. DOI: 10.1021/bc1003108

  20. Increased efficacies of an individual catalytic site in clustered multivalent dendritic catalysts: N. Jayaraman, (2009) Adv. Synth. Catal., 351: 2379–2390. DOI: 10.1002/adsc.200900377

  21. Preparation and catalytic studies of palladium nanoparticles stabilized by a dendritic ligand-functionalized Silica: C. P. Umesh, N. Jayaraman, (2009) J. Mol. Catal. A: Chem, 307: 142–148. DOI: 10.1016/j.molcata.2009.03.020

  22. Inherent photoluminescence properties of poly(propyl ether imine) dendrimers: C. P. Umesh, N. Jayaraman, (2008) Org. Lett., 10: 9–12. DOI: 10.1021/ol702635w

  23. Structure of poly(propyl ether imine) dendrimer from fully atomistic molecular dynamics simulation and by small angle X-ray scattering: R. Ganapathy, P. K. Maiti, N. Jayaraman, A. K. Sood,C. Jana, (2006) J. Chem. Phys., 124: 204719/1–204719/10. DOI: 10.1063/1.2194538

  24. Synthesis of large generation poly(propyl ether imine) (PETIM) dendrimers: N. Jayaraman, (2006) Tetrahedron, 62: 9582–9588. DOI: 10.1016/j.tet.2006.07.094

  1. Tuning of the Cross-Glaser Products mediated by Substrate-Catalyst’s Polymeric Backbone Interactions: S. Kuar, A. Mukhopadhyaya, A. Selim, V. Gowri, K. M. Neethu, A. H. Dar, S. Sartaliya, M. E. Ali*, G. Jayamurugan*, (2020) Chem. Commun., 56: 2582-2585. DOI: 10.1039/C9CC08565C

  1. Dendrimer-metal nanocomposites and their optical behavior: In Nanotechnological Applications of Novel polymers; Adeli, M., Ed.; Transworld Research Network: Trivandrum, B. M. Kiran,N. Jayaraman, (2009) 105–131.

  1. Non-planar push-pull chromophores for detection of fluoride (F–) and method of preparing the same: G. Jayamurugan,* V. Gowri, S. Jalwal, A. H. Dar, (2020) Indian Patent No, 202011028595. DOI: 202011028595

  2. Thiol functionalized polymers bearing catalytic nanoparticles method of preparing the same and use thereof: G. Jayamurugan,* A. Selim, S. Kaur, K. M. Neethu, V. Gowri, M. E. Ali, (2019) Patent no. 201911042361.

  3. Poly(ether imine) dendrimers and uses thereof: Indian pat. Appl. IN2010CH04010, N. Jayaraman, (2014) 64.

  4. “New poly(ether imine) dendrimers useful in preparing polymer system for deleivering negatively charged moleucle e.g. nucliec acid, DNA, polynucleotides, short interfering RNA, micro RNA and : PCT Int. Appl. WO 2012090223-A1 N. Jayaraman, P. U. Thankappan, N. S. Madhusudana, A. Desai,Yamajala B. R. D. Rajesh, (2012) .

  5. A method for detecting an analyte: US patent App, US 20120171776 N. Jayaraman,Y. B. R. D. Rajesh, R. Bhaskara, B. Suresh, A. K. Sood, (2011) 18.

  1. Applying synthetic lethality to nanomedicine: LCS-1 loaded magnetite and polymeric nanoparticles for the treatment of BLM and CHEK2-deficient colorectal cancer cells: In CANCER MEDICINE 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY A. Gupta, Ahmad A, (2018) 7: 27-28.

  2. CuI/IIO Nanoparticles-Grafted Tailor-made Cellulose as an Efficient Catalyst for “Glaser” Homo- and Hetero-coupling Reactions “First INST-CeNS Joint symposium,: Hampi, (2017) .

  3. Customized Nanocarrier for Therapeutic Targeting of Cancer Cells, DBT workshop for biotechnology school: organized by INST at NABI, (2017) .

  4. Biocompatible hyperbranched polymers coated magnetite nanocarrier for therapeutic targeting of cancer cells National Conference on Trends in Nanobiotechnology (NCTN-2016): CCS Haryana Agricultural University, Hisar, India, (2016) .

  5. Fulvenoid, nonplanar push-pull chromophores: Poster presentation at the Electronic Process in Organic Materials Gordon Conference, Lucca, Italy, J.-P. Gisselbrecht, C. Boudon, W. B. Schweizer, F. Diederich,A. D. Finke, O. Dumele, (2012) .

  6. Swiss Chemical Society: ETH-Zurich / Switzerland _ Poster: “Diverse Chemical Reactivity of Push-Pull type Fulvene with Electron Rich Alkynes O. Dumele, W. B. Schweizer, B. Bernet, J.-P. Gisselbrecht, C. Boudon, F. Diederich, (2011) .

  7. Wisenshaftforumchemie: Expanding the Chemical Space for Push-Pull chromophores by Non-concerted [2+2] and [4+2] Cycloadditions: Access to a Highly Functionalized 6,6-dicyanopentafulvene with Attractive Opto-electronic Properties F. Schoenebeck, W. B. Schweizer, B. Bernet, J.-P. Gisselbrecht, C. Boudon, F. Diederich, (2011) .

  8. 3rd EuCheMS Chemistry Congress: Nürnberg / Germany _ Poster: “Synthesis and Studies of Chiral and Achiral Push-Pull Type Charge-Transfer Chromophores Derived from Different Oligoyne” B. B. Frank, M. Kivala, W. B. Schweizer, B. C. Blanco, B. Breiten, R. R. Tykwinski, E. Jahnke, C. Boudon, J.-P. Gisselbrecht, F. Diederich, (2010) .

  9. Synthesis and Studies of Poly(Ether Imine) (PETIM) Dendritic Macromolecules: National Conference on Chemistry,Bangalore University, Bangalore, India. N. Jayaraman, (2006) .

  10. International Symposium in Organic Chemistry: IISc, Bangalore, India _ Poster Presentation: “Synthesis and Fluorescence Studies of Poly(Propyl Ether Imine) (PETIM) Dendrimers”. N. Jayaraman, (2005) .

Fundings

  • Utilization of Rice Residues for Value Added Product Development 3 years, DBT
    Funding Amount: 76.4
    PI: Dr. Jayamurugan Govindasamy
  • Synthesis of a New Class of Strong Organic Acceptors and their Nanoparticles Formulation for Sensing Application 3.5 years, DST-SERB
    Funding Amount: 24.14
    PI: Dr. Jayamurugan Govindasamy
  • Design, Synthesis and Applications of Functional Organic Nanomaterials 5 years, DST-SERB
    Funding Amount: 38
    PI: Dr. Jayamurugan Govindasamy
  • Dual-Drug loaded Customized Nanocarrier for Synergistic Synthetic Lethal killing of colorectal Cancer (As Co-PI) 2017-2019, DST-Nanomission
    Funding Amount: 19 Lakhs
    PI: Dr. Jayamurugan Govindasamy
  • As WOS-B on ‘Encapsulation of pesticides by magnetic nanoparticles coated with polysaccharide to improve the input delivery’ , INST, Mohali 3 years, DST
    Funding Amount: 31,58,400/-
    Role PI: Dr. Ritu Mahajan Role Co-PI: Dr. Jayamurugan Govindasamy

  • 2009

    Ph.D

    Department of Organic Chemistry, Indian Institute of Science (IISc), Bangalore, India

  • 2003

    M.Sc

    Organic Chemistry (specialization), University of Madras, Chennai, India

  • 2001

    B.Sc

    University of Madras, India

  • Assistant Professor (Scientist-D):Institute of Nano Science and Technology,, Mohali, India (June 2015 to Present till date )

  • Postdoctoral Research Associate:University of Cambridge,, United Kingdom. (January 2013 to May 2015 )

  • Postdoctoral Fellow:ETH-Zurich, . (PI: Prof. François Diederich), Switzerland (January 2010 to December 2012 )

  • Research Associate:Indian Institute of Science, (PI: Prof. N. Jayaraman), Bangalore, India (April 2009 to December 2009 )

Awards & Honours

  • Ramanujan Fellowship awarded by DST-SERB-five year research grant (2016-2021)
  • Early Career Research (ECR) Award by SERB-three year research grant (2016-2019)
  • Two and half year’s post-doctoral fellowship sponsored by EPSRC at University of Cambridge.(2012)
  • Three years post-doctoral fellowship sponsored by European Research Council (ERC) at ETH-Zurich.(2010)
  • Awarded Senior Research Fellowship (SRF) by Council of Scientific Industrial Research.(2005)
  • Secured second place in State level inter collegiate P. G. quiz competition.(2003)
  • Qualified in national eligibility test “CSIR-NET-2003”. Awarded Junior Research Fellowship (JRF) by Council of Scientific Industrial Research
  • Secured 95.5 percentile in national level Graduate Aptitude Test in Engineering “GATE-2002”

Professional Recognitions