PcG Epigenetics & Colorectal Cancer

Hypericin-Loaded Transferrin Nanoparticles Induce PP2A-Regulated BMI1 Degradation in Colorectal Cancer-Specific Chemo-Photodynamic Therapy

Dr. Subhasree Roy Choudhury and group have shown targeted photodynamic therapy (PDT) with potential photosessitizer nanocomposite inducing PP2A-mediated BMI1 ubiquitination/degradation demonstrating an epigenetic driven nanotherapeutic approach in colorectal cancer treatment.

 

More details: ACS Biomater. Sci. Eng. 2020, 6, 5, 3139–3153. https://doi.org/10.1021/acsbiomaterials.9b01844

PcG Epigenetics & Colorectal Cancer